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Intractable and Refactory Pain | PainSolve
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Updates & Features

Lack of clear and consistent definition for chronic neuropathic intractable or refractory pain

October 2018

What are the implications for a lack of a clear definition?

PainSolve Editorial Team

Unmet need in chronic neuropathic pain treatment

Most patients with chronic neuropathic pain are treated with medications as the mainstay of therapy, and yet most medically treated patients continue to report ongoing pain. A recent evidence-based review of medical therapy for neuropathic pain concluded that “existing pharmacologic treatments for neuropathic pain are limited, with no more than 40-60% of patients obtaining partial relief of their pain.”1 This means that roughly half of all patients with common conditions, such as diabetic peripheral neuropathy, lumbar radiculopathy or postsurgical neuropathic pain will not have sufficient improvement with conservative pain care measures.2

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